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2-thio-6-azauridine inhibits Vpu mediated BST-2 degradation

BACKGROUD: BST-2 is an interferon-induced host restriction factor that inhibits the release of diverse mammalian enveloped viruses from infected cells by physically trapping the newly formed virions onto the host cell surface. Human Immunodeficiency Virus-1 (HIV-1) encodes an accessory protein Vpu t...

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Detalles Bibliográficos
Autores principales: Zhang, Quan, Mi, Zeyun, Huang, Yuming, Ma, Ling, Ding, Jiwei, Wang, Jing, Zhang, Yongxin, chen, Yang, Zhou, Jinming, Guo, Fei, Li, Xiaoyu, Cen, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776379/
https://www.ncbi.nlm.nih.gov/pubmed/26935098
http://dx.doi.org/10.1186/s12977-016-0247-z