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2-thio-6-azauridine inhibits Vpu mediated BST-2 degradation
BACKGROUD: BST-2 is an interferon-induced host restriction factor that inhibits the release of diverse mammalian enveloped viruses from infected cells by physically trapping the newly formed virions onto the host cell surface. Human Immunodeficiency Virus-1 (HIV-1) encodes an accessory protein Vpu t...
Autores principales: | Zhang, Quan, Mi, Zeyun, Huang, Yuming, Ma, Ling, Ding, Jiwei, Wang, Jing, Zhang, Yongxin, chen, Yang, Zhou, Jinming, Guo, Fei, Li, Xiaoyu, Cen, Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776379/ https://www.ncbi.nlm.nih.gov/pubmed/26935098 http://dx.doi.org/10.1186/s12977-016-0247-z |
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