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Oxford Lithium Trial (OxLith) of the early affective, cognitive, neural and biochemical effects of lithium carbonate in bipolar disorder: study protocol for a randomised controlled trial

BACKGROUND: Despite lithium’s being the most effective drug for bipolar disorder and in clinical use for decades, we still know very little about its early effects relevant to its mode of action. METHODS/DESIGN: The Oxford Lithium Trial is a double-blind, randomised, placebo-controlled study of 6-we...

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Detalles Bibliográficos
Autores principales: Saunders, Kate E. A., Cipriani, Andrea, Rendell, Jennifer, Attenburrow, Mary-Jane, Nelissen, Natalie, Bilderbeck, Amy C., Vasudevan, Sridhar R., Churchill, Grant, Goodwin, Guy M., Nobre, Anna C., Harmer, Catherine J., Harrison, Paul J., Geddes, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776410/
https://www.ncbi.nlm.nih.gov/pubmed/26936776
http://dx.doi.org/10.1186/s13063-016-1230-7