Exome screening to identify loss-of-function mutations in the rhesus macaque for development of preclinical models of human disease

BACKGROUND: Exome sequencing has been utilized to identify genetic variants associated with disease in humans. Identification of loss-of-function mutations with exome sequencing in rhesus macaques (Macaca mulatta) could lead to valuable animal models of genetic disease. Attempts have been made to id...

Descripción completa

Detalles Bibliográficos
Autores principales: Cornish, Adam S., Gibbs, Robert M., Norgren, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776415/
https://www.ncbi.nlm.nih.gov/pubmed/26935327
http://dx.doi.org/10.1186/s12864-016-2509-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776415/
https://www.ncbi.nlm.nih.gov/pubmed/26935327
http://dx.doi.org/10.1186/s12864-016-2509-5

Ejemplares similares