Exome screening to identify loss-of-function mutations in the rhesus macaque for development of preclinical models of human disease

BACKGROUND: Exome sequencing has been utilized to identify genetic variants associated with disease in humans. Identification of loss-of-function mutations with exome sequencing in rhesus macaques (Macaca mulatta) could lead to valuable animal models of genetic disease. Attempts have been made to id...

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Detalles Bibliográficos
Autores principales: Cornish, Adam S., Gibbs, Robert M., Norgren, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776415/
https://www.ncbi.nlm.nih.gov/pubmed/26935327
http://dx.doi.org/10.1186/s12864-016-2509-5

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