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Motif mediated protein-protein interactions as drug targets

Protein-protein interactions (PPI) are involved in virtually every cellular process and thus represent an attractive target for therapeutic interventions. A significant number of protein interactions are frequently formed between globular domains and short linear peptide motifs (DMI). Targeting thes...

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Detalles Bibliográficos
Autores principales: Corbi-Verge, Carles, Kim, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776425/
https://www.ncbi.nlm.nih.gov/pubmed/26936767
http://dx.doi.org/10.1186/s12964-016-0131-4