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Susceptibility of brown adipocytes to pro-inflammatory cytokine toxicity and reactive oxygen species

Brown adipose tissue (BAT) cells have a very high oxidative capacity. On the other hand, in obesity and obesity-related diabetes, levels of pro-inflammatory cytokines are elevated, which might promote BAT dysfunction and consequently impair carbohydrate metabolism and thereby exacerbate cellular dys...

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Detalles Bibliográficos
Autores principales: Rebiger, Lars, Lenzen, Sigurd, Mehmeti, Ilir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776627/
https://www.ncbi.nlm.nih.gov/pubmed/26795216
http://dx.doi.org/10.1042/BSR20150193