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Direct spectrophotometric measurement of supra-physiological levels of ascorbate in plasma

BACKGROUND: Supra-physiological concentrations of ascorbate, vitamin C, in blood, greater than 1 mM, achieved through intravenous administration (IV), are being tested in clinical trials to treat human disease, e.g. cancer. These trials need information on the high levels of ascorbate achieved in bl...

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Detalles Bibliográficos
Autores principales: Witmer, Jordan R., Wetherell, Bailey J., Wagner, Brett A., Du, Juan, Cullen, Joseph J., Buettner, Garry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776628/
https://www.ncbi.nlm.nih.gov/pubmed/26928133
http://dx.doi.org/10.1016/j.redox.2016.02.004