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Direct spectrophotometric measurement of supra-physiological levels of ascorbate in plasma
BACKGROUND: Supra-physiological concentrations of ascorbate, vitamin C, in blood, greater than 1 mM, achieved through intravenous administration (IV), are being tested in clinical trials to treat human disease, e.g. cancer. These trials need information on the high levels of ascorbate achieved in bl...
Autores principales: | Witmer, Jordan R., Wetherell, Bailey J., Wagner, Brett A., Du, Juan, Cullen, Joseph J., Buettner, Garry R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776628/ https://www.ncbi.nlm.nih.gov/pubmed/26928133 http://dx.doi.org/10.1016/j.redox.2016.02.004 |
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