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Tumour Cell Heterogeneity

The population of cells that make up a cancer are manifestly heterogeneous at the genetic, epigenetic, and phenotypic levels. In this mini-review, we summarise the extent of intra-tumour heterogeneity (ITH) across human malignancies, review the mechanisms that are responsible for generating and main...

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Detalles Bibliográficos
Autores principales: Gay, Laura, Baker, Ann-Marie, Graham, Trevor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776671/
https://www.ncbi.nlm.nih.gov/pubmed/26973786
http://dx.doi.org/10.12688/f1000research.7210.1