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Evolutionary Transition of Promoter and Gene Body DNA Methylation across Invertebrate–Vertebrate Boundary

Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is mostly targeted to a subset of transcription units (gene bodies). In a drastic contrast, vertebrate genomes are generally globall...

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Detalles Bibliográficos
Autores principales: Keller, Thomas E., Han, Priscilla, Yi, Soojin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776710/
https://www.ncbi.nlm.nih.gov/pubmed/26715626
http://dx.doi.org/10.1093/molbev/msv345