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Whole-Genome Sequencing of a Canine Family Trio Reveals a FAM83G Variant Associated with Hereditary Footpad Hyperkeratosis

Over 250 Mendelian traits and disorders, caused by rare alleles have been mapped in the canine genome. Although each disease is rare in the dog as a species, they are collectively common and have major impact on canine health. With SNP-based genotyping arrays, genome-wide association studies (GWAS)...

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Detalles Bibliográficos
Autores principales: Sayyab, Shumaila, Viluma, Agnese, Bergvall, Kerstin, Brunberg, Emma, Jagannathan, Vidhya, Leeb, Tosso, Andersson, Göran, Bergström, Tomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777115/
https://www.ncbi.nlm.nih.gov/pubmed/26747202
http://dx.doi.org/10.1534/g3.115.025643