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Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans

Inappropriate activation of innate immune responses in intestinal epithelial cells underlies the pathophysiology of inflammatory disorders of the intestine. Here we examine the physiological effects of immune hyperactivation in the intestine of the nematode Caenorhabditis elegans. We previously iden...

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Detalles Bibliográficos
Autores principales: Cheesman, Hilary K., Feinbaum, Rhonda L., Thekkiniath, Jose, Dowen, Robert H., Conery, Annie L., Pukkila-Worley, Read
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777117/
https://www.ncbi.nlm.nih.gov/pubmed/26818074
http://dx.doi.org/10.1534/g3.115.025650