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Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans
Inappropriate activation of innate immune responses in intestinal epithelial cells underlies the pathophysiology of inflammatory disorders of the intestine. Here we examine the physiological effects of immune hyperactivation in the intestine of the nematode Caenorhabditis elegans. We previously iden...
Autores principales: | Cheesman, Hilary K., Feinbaum, Rhonda L., Thekkiniath, Jose, Dowen, Robert H., Conery, Annie L., Pukkila-Worley, Read |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777117/ https://www.ncbi.nlm.nih.gov/pubmed/26818074 http://dx.doi.org/10.1534/g3.115.025650 |
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