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Isolation of a Hypomorphic skn-1 Allele That Does Not Require a Balancer for Maintenance

In Caenorhabditis elegans, the transcription factor SKN-1 has emerged as a central coordinator of stress responses and longevity, increasing the need for genetic tools to study its regulation and function. However, current loss-of-function alleles cause fully penetrant maternal effect embryonic leth...

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Detalles Bibliográficos
Autores principales: Tang, Lanlan, Dodd, William, Choe, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777118/
https://www.ncbi.nlm.nih.gov/pubmed/26715089
http://dx.doi.org/10.1534/g3.115.023010