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Novel Heterotypic Rox Sites for Combinatorial Dre Recombination Strategies

Site-specific recombinases (SSRs) such as Cre are widely used in gene targeting and genetic approaches for cell labeling and manipulation. They mediate DNA strand exchange between two DNA molecules at dedicated recognition sites. Precise understanding of the Cre recombination mechanism, including th...

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Detalles Bibliográficos
Autores principales: Chuang, Katherine, Nguyen, Eileen, Sergeev, Yuri, Badea, Tudor C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777119/
https://www.ncbi.nlm.nih.gov/pubmed/26715092
http://dx.doi.org/10.1534/g3.115.025841