Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma

Methylation of the O(6)-methylguanine-DNA methyltransferase (MGMT) gene is a predictive and prognostic marker in newly diagnosed glioblastoma patients treated with temozolomide but how MGMT methylation should be assessed to ensure optimal detection accuracy is debated. We developed a novel quantitat...

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Detalles Bibliográficos
Autores principales: Kristensen, Lasse S., Michaelsen, Signe R., Dyrbye, Henrik, Aslan, Derya, Grunnet, Kirsten, Christensen, Ib J., Poulsen, Hans S., Grønbæk, Kirsten, Broholm, Helle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777218/
https://www.ncbi.nlm.nih.gov/pubmed/26883115
http://dx.doi.org/10.1093/jnen/nlv024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777218/
https://www.ncbi.nlm.nih.gov/pubmed/26883115
http://dx.doi.org/10.1093/jnen/nlv024

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