Slow drug delivery decreased total body clearance and altered bioavailability of immediate‐ and controlled‐release oxycodone formulations

Oxycodone is a commonly used analgesic with a large body of pharmacokinetic data from various immediate‐release or controlled‐release formulations, under different administration routes, and in diverse populations. Longer terminal half‐lives from extravascular administration as compared to IV admini...

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Detalles Bibliográficos
Autores principales: Li, Yan, Sun, Duxin, Palmisano, Maria, Zhou, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777261/
https://www.ncbi.nlm.nih.gov/pubmed/26977300
http://dx.doi.org/10.1002/prp2.210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777261/
https://www.ncbi.nlm.nih.gov/pubmed/26977300
http://dx.doi.org/10.1002/prp2.210

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