Lack of cross‐resistance to FF‐10501, an inhibitor of inosine‐5′‐monophosphate dehydrogenase, in azacitidine‐resistant cell lines selected from SKM‐1 and MOLM‐13 leukemia cell lines

Resistance to azacitidine is a major issue in the treatments of myelodysplastic syndrome and acute myeloid leukemia, and previous studies suggest that changes in drug metabolism are involved in the resistance. Therefore, drugs with mechanisms resistant or alternative to such metabolic changes have b...

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Detalles Bibliográficos
Autores principales: Murase, Motohiko, Iwamura, Hiroyuki, Komatsu, Kensuke, Saito, Motoki, Maekawa, Toshihiko, Nakamura, Takaaki, Yokokawa, Takuya, Shimada, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777262/
https://www.ncbi.nlm.nih.gov/pubmed/26977297
http://dx.doi.org/10.1002/prp2.206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777262/
https://www.ncbi.nlm.nih.gov/pubmed/26977297
http://dx.doi.org/10.1002/prp2.206

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