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Pharmacological comparison of a nonhuman primate and a rat model of oxaliplatin‐induced neuropathic cold hypersensitivity

Oxaliplatin is a first‐line treatment for colorectal cancer. However, shortly following treatment, cold‐evoked hypersensitivity appears in the extremities and over time, the pain is such that oxaliplatin dosing may need to be markedly reduced or even terminated. There is currently a lack of efficaci...

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Detalles Bibliográficos
Autores principales: Shidahara, Yuka, Ogawa, Shinya, Nakamura, Mari, Nemoto, Shingo, Awaga, Yuji, Takashima, Miyuki, Hama, Aldric, Matsuda, Akihisa, Takamatsu, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777264/
https://www.ncbi.nlm.nih.gov/pubmed/26977304
http://dx.doi.org/10.1002/prp2.216