Molecular modeling of antibodies for the treatment of TNF α‐related immunological diseases

Therapeutic monoclonal antibodies (mAbs) have high efficacy in treating TNF α‐related immunological diseases. Other than neutralizing TNF α, these IgG1 antibodies exert Fc receptor‐mediated effector functions such as the complement‐dependent cytotoxicity (CDC) and antibody‐dependent cell cytotoxicit...

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Detalles Bibliográficos
Autores principales: Pierri, Ciro Leonardo, Bossis, Fabrizio, Punzi, Giuseppe, De Grassi, Anna, Cetrone, Michela, Parisi, Giovanni, Tricarico, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777268/
https://www.ncbi.nlm.nih.gov/pubmed/26977294
http://dx.doi.org/10.1002/prp2.197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777268/
https://www.ncbi.nlm.nih.gov/pubmed/26977294
http://dx.doi.org/10.1002/prp2.197

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