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Update on the management of Philadelphia chromosome positive chronic myelogenous leukemia: role of nilotinib
Chronic myelogenous leukemia (CML) is a pluripotent stem cell disease characterized by the presence of the Philadelphia chromosome and the bcr-abl gene. The discovery of tyrosine kinase inhibitors (TKIs) revolutionized therapy for CML, such that durable response, increased overall survival, and incr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777272/ https://www.ncbi.nlm.nih.gov/pubmed/27013862 http://dx.doi.org/10.2147/BTT.S67844 |