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Atg7 Knockdown Augments Concanavalin A-Induced Acute Hepatitis through an ROS-Mediated p38/MAPK Pathway

Concanavalin A (ConA), a T-cell mitogen that induces acute autoimmune hepatitis, is widely used to model pathophysiological processes of human acute autoimmune liver disease. Although autophagy has been extensively studied in the past decade, little is known about its molecular mechanism underlying...

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Detalles Bibliográficos
Autores principales: Zhuang, Yan, Li, Yi, Li, Xuefeng, Xie, Qing, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777387/
https://www.ncbi.nlm.nih.gov/pubmed/26939081
http://dx.doi.org/10.1371/journal.pone.0149754