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Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth

The persistence of a reservoir of latently infected CD4 T cells remains one of the major obstacles to cure HIV. Numerous strategies are being explored to eliminate this reservoir. To translate these efforts into clinical trials, there is a strong need for validated biomarkers that can monitor the re...

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Detalles Bibliográficos
Autores principales: Kiselinova, Maja, De Spiegelaere, Ward, Buzon, Maria Jose, Malatinkova, Eva, Lichterfeld, Mathias, Vandekerckhove, Linos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777389/
https://www.ncbi.nlm.nih.gov/pubmed/26938995
http://dx.doi.org/10.1371/journal.ppat.1005472