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Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody

Enterovirus 71 (EV71) is the main pathogen responsible for hand, foot and mouth disease with severe neurological complications and even death in young children. We have recently identified a highly potent anti-EV71 neutralizing monoclonal antibody, termed D5. Here we investigated the structural basi...

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Detalles Bibliográficos
Autores principales: Ye, Xiaohua, Fan, Chen, Ku, Zhiqiang, Zuo, Teng, Kong, Liangliang, Zhang, Chao, Shi, Jinping, Liu, Qingwei, Chen, Tan, Zhang, Yingyi, Jiang, Wen, Zhang, Linqi, Huang, Zhong, Cong, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777393/
https://www.ncbi.nlm.nih.gov/pubmed/26938634
http://dx.doi.org/10.1371/journal.ppat.1005454