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Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism

BAHD1 is a vertebrate protein that promotes heterochromatin formation and gene repression in association with several epigenetic regulators. However, its physiological roles remain unknown. Here, we demonstrate that ablation of the Bahd1 gene results in hypocholesterolemia, hypoglycemia and decrease...

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Detalles Bibliográficos
Autores principales: Lakisic, Goran, Lebreton, Alice, Pourpre, Renaud, Wendling, Olivia, Libertini, Emanuele, Radford, Elizabeth J., Le Guillou, Morwenna, Champy, Marie-France, Wattenhofer-Donzé, Marie, Soubigou, Guillaume, Ait-Si-Ali, Slimane, Feunteun, Jean, Sorg, Tania, Coppée, Jean-Yves, Ferguson-Smith, Anne C., Cossart, Pascale, Bierne, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777444/
https://www.ncbi.nlm.nih.gov/pubmed/26938916
http://dx.doi.org/10.1371/journal.pgen.1005898