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TCDD-Induced Activation of Aryl Hydrocarbon Receptor Inhibits Th17 Polarization and Regulates Non-Eosinophilic Airway Inflammation in Asthma

The aryl hydrocarbon receptor (AhR), a transcription factor of the bHLH/PAS family, has recently been demonstrated to regulate T cell differentiation. Whether AhR activation participates in allergic airway inflammation remains unknown. In the current study, using a non-eosinophilic asthma model, we...

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Detalles Bibliográficos
Autores principales: Li, Xiao-ming, Peng, Juan, Gu, Wen, Guo, Xue-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777447/
https://www.ncbi.nlm.nih.gov/pubmed/26938767
http://dx.doi.org/10.1371/journal.pone.0150551