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Identifying Likely Transmission Pathways within a 10-Year Community Outbreak of Tuberculosis by High-Depth Whole Genome Sequencing

BACKGROUND: Improved tuberculosis control and the need to contain the spread of drug-resistant strains provide a strong rationale for exploring tuberculosis transmission dynamics at the population level. Whole-genome sequencing provides optimal strain resolution, facilitating detailed mapping of pot...

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Detalles Bibliográficos
Autores principales: Outhred, Alexander C., Holmes, Nadine, Sadsad, Rosemarie, Martinez, Elena, Jelfs, Peter, Hill-Cawthorne, Grant A., Gilbert, Gwendolyn L., Marais, Ben J., Sintchenko, Vitali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777479/
https://www.ncbi.nlm.nih.gov/pubmed/26938641
http://dx.doi.org/10.1371/journal.pone.0150550