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Genetic Correlations Greatly Increase Mutational Robustness and Can Both Reduce and Enhance Evolvability

Mutational neighbourhoods in genotype-phenotype (GP) maps are widely believed to be more likely to share characteristics than expected from random chance. Such genetic correlations should strongly influence evolutionary dynamics. We explore and quantify these intuitions by comparing three GP maps—a...

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Detalles Bibliográficos
Autores principales: Greenbury, Sam F., Schaper, Steffen, Ahnert, Sebastian E., Louis, Ard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777517/
https://www.ncbi.nlm.nih.gov/pubmed/26937652
http://dx.doi.org/10.1371/journal.pcbi.1004773