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Involvement of Polycomb Repressive Complex 2 in Maturation of Induced Pluripotent Stem Cells during Reprogramming of Mouse and Human Fibroblasts

Induced pluripotent stem cells (iPSCs) provide a reliable source for the study of regenerative medicine, drug discovery, and developmental biology. Despite extensive studies on the reprogramming of mouse and human fibroblasts into iPSCs, the efficiency of reprogramming is still low. Here, we used a...

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Detalles Bibliográficos
Autores principales: Khazaie, Niusha, Massumi, Mohammad, Wee, Ping, Salimi, Mahdieh, Mohammadnia, Abdulshakour, Yaqubi, Moein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777544/
https://www.ncbi.nlm.nih.gov/pubmed/26938987
http://dx.doi.org/10.1371/journal.pone.0150518