PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma

Sonic hedgehog (SHH) medulloblastoma (MB) subtype is driven by a proliferative CD15+ tumor propagating cell (TPC), also considered in the literature as a putative cancer stem cell (CSC). Despite considerable research, much of the biology of this TPC remains unknown. We report evidence that phosphata...

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Detalles Bibliográficos
Autores principales: Singh, Alok R., Joshi, Shweta, Zulcic, Muamera, Alcaraz, Michael, Garlich, Joseph R., Morales, Guillermo A., Cho, Yoon J., Bao, Lei, Levy, Michael L., Newbury, Robert, Malicki, Denise, Messer, Karen, Crawford, John, Durden, Donald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777592/
https://www.ncbi.nlm.nih.gov/pubmed/26938241
http://dx.doi.org/10.1371/journal.pone.0150836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777592/
https://www.ncbi.nlm.nih.gov/pubmed/26938241
http://dx.doi.org/10.1371/journal.pone.0150836

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