A novel intranuclear RNA vector system for long-term stem cell modification

Genetically modified stem and progenitor cells have emerged as a promising regenerative platform in the treatment of genetic and degenerative disorders, highlighted by their successful therapeutic use in inherent immunodeficiencies. However, biosafety concerns over insertional mutagenesis resulting...

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Detalles Bibliográficos
Autores principales: Ikeda, Yasuhiro, Makino, Akiko, Matchett, William E., Holditch, Sara J., Lu, Brian, Dietz, Allan B., Tomonaga, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777691/
https://www.ncbi.nlm.nih.gov/pubmed/26632671
http://dx.doi.org/10.1038/gt.2015.108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777691/
https://www.ncbi.nlm.nih.gov/pubmed/26632671
http://dx.doi.org/10.1038/gt.2015.108

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