Cargando…

A novel intranuclear RNA vector system for long-term stem cell modification

Genetically modified stem and progenitor cells have emerged as a promising regenerative platform in the treatment of genetic and degenerative disorders, highlighted by their successful therapeutic use in inherent immunodeficiencies. However, biosafety concerns over insertional mutagenesis resulting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikeda, Yasuhiro, Makino, Akiko, Matchett, William E., Holditch, Sara J., Lu, Brian, Dietz, Allan B., Tomonaga, Keizo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777691/ https://www.ncbi.nlm.nih.gov/pubmed/26632671 http://dx.doi.org/10.1038/gt.2015.108

Ejemplares similares

RNA Virus-Based Episomal Vector with a Fail-Safe Switch Facilitating Efficient Genetic Modification and Differentiation of iPSCs
por: Komatsu, Yumiko, et al.
Publicado: (2019)

Long-term expression of miRNA for RNA interference using a novel vector system based on a negative-strand RNA virus
por: Honda, Tomoyuki, et al.
Publicado: (2016)

Dual function of the nuclear export signal of the Borna disease virus nucleoprotein in nuclear export activity and binding to viral phosphoprotein
por: Yanai, Mako, et al.
Publicado: (2017)

Evolutionary Selection of the Nuclear Localization Signal in the Viral Nucleoprotein Leads to Host Adaptation of the Genus Orthobornavirus
por: Komorizono, Ryo, et al.
Publicado: (2020)

Borna disease virus possesses an NF-ĸB inhibitory sequence in the nucleoprotein gene
por: Makino, Akiko, et al.
Publicado: (2015)

Myoclonic Epilepsy with Ragged-red Fibers with Intranuclear Inclusions
por: Kawazoe, Tomoya, et al.
Publicado: (2021)

ON THE NATURE OF INTRANUCLEAR RODS
por: Colonnier, M.
Publicado: (1965)

Intranuclear Microinjection of DNA into Dissociated Adult Mammalian Neurons
por: Lu, Van B., et al.
Publicado: (2009)

Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression
por: Yamamoto, Yusuke, et al.
Publicado: (2019)

Intranuclear changes in cancer cells
por: Gilbert, David M, et al.
Publicado: (2007)

The behaviour of generons in intranuclear matter
por: Strugalski, Z, et al.
Publicado: (1993)

In vivo biodistribution analysis of transmission competent and defective RNA virus-based episomal vector
por: Komatsu, Yumiko, et al.
Publicado: (2020)

Radioligand Assay-Based Detection of Antibodies against SARS-CoV-2 in Hospital Workers Treating Patients with Severe COVID-19 in Japan
por: Matsunaga, Hidenori, et al.
Publicado: (2021)

Intranuclear birefringent inclusions in paraffin sections by polychromatic polarization microscopy
por: Vitkunaite, Aiste, et al.
Publicado: (2021)

Intranuclear localization of snRNP antigens
Publicado: (1986)

INTRANUCLEAR ANNULATE LAMELLAE IN ASCIDIAN EMBRYOS
por: Everingham, John W.
Publicado: (1968)

Hadrons as probes for exploration into intranuclear matter
por: Strugalski, Z, et al.
Publicado: (1996)

Arterial Remodeling in B-Type Natriuretic Peptide Knock-Out Females
por: Holditch, Sara J., et al.
Publicado: (2016)

Contact-number-driven virus evolution: A multi-level modeling framework for the evolution of acute or persistent RNA virus infection
por: Sunagawa, Junya, et al.
Publicado: (2023)

Probing Intranuclear Environments at the Single-Molecule Level
por: Grünwald, David, et al.
Publicado: (2008)

INTRANUCLEAR CISTERNAE RESEMBLING STRUCTURES OF THE GOLGI COMPLEX
por: Bucciarelli, Emilio
Publicado: (1966)

INTRANUCLEAR AND CYTOPLASMIC ANNULATE LAMELLAE IN TUNICATE OOCYTES
por: Kessel, R. G.
Publicado: (1965)

ATTACHMENT OF INTRANUCLEAR ANNULATE LAMELLAE TO THE NUCLEAR ENVELOPE
por: Everingham, John W.
Publicado: (1968)

THE EFFECT OF PUROMYCIN ON INTRANUCLEAR STEPS IN RIBOSOME BIOSYNTHESIS
por: Soeiro, R., et al.
Publicado: (1968)

INTRANUCLEAR AND CYTOPLASMIC ANNULATE LAMELLAE IN PLANT CELLS
por: Franke, Werner W., et al.
Publicado: (1972)

INTRANUCLEAR RODS IN PANCREATIC ISLET β-CELLS
por: Boquist, Lennart
Publicado: (1969)

Intranuclear dynamics of the Nup107-160 complex
por: Morchoisne-Bolhy, Stéphanie, et al.
Publicado: (2015)

NSort/DB: An Intranuclear Compartment Protein Database
por: Willadsen, Kai, et al.
Publicado: (2012)

Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins
por: Iyama, Teruaki, et al.
Publicado: (2018)

Cytoplasmic control of intranuclear polarity by human cytomegalovirus
por: Procter, Dean J, et al.
Publicado: (2020)

Neuronal intranuclear inclusion disease is genetically heterogeneous
por: Chen, Zhongbo, et al.
Publicado: (2020)

The long noncoding RNA SPRIGHTLY acts as an intranuclear organizing hub for pre-mRNA molecules
por: Lee, Bongyong, et al.
Publicado: (2017)

Intranuclear cascading at ultrahigh energy in heavy-ion interactions
por: Jain, P L, et al.
Publicado: (1991)

Intranuclear complexes in a copper-tolerant green alga
Publicado: (1976)

A LABILE INTRANUCLEAR RNA ASSOCIATED WITH THE DEVELOPMENT OF ADENOVIRUSES
por: Mayor, Heather Donald
Publicado: (1964)

INTRANUCLEAR CRYSTAL WITHIN THE PHAGOCYTES OF THE OVARY OF ARBACIA PUNCTULATA
por: Karasaki, Shuichi
Publicado: (1965)

INTRANUCLEAR FIBRILLAR BODIES IN ACTINOMYCIN D-TREATED OOCYTES
por: Lane, Nancy J.
Publicado: (1969)

Separation of intranuclear cascade effects in neutrino-neon interactions
por: Vataga, E S
Publicado: (1996)

Observations of fast hadron passages through intranuclear matter
por: Strugalska-Gola, E, et al.
Publicado: (1994)

Essential tremor with ubiquitinated intranuclear inclusions and cerebellar degeneration
por: Louis, Elan D., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_nvtm0rghu5vqksking8g8r8k2u