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FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas

The FOXP1 (forkhead box P1) transcription factor is a marker of poor prognosis in diffuse large B-cell lymphoma (DLBCL). Here microarray analysis of FOXP1-silenced DLBCL cell lines identified differential regulation of immune response signatures and major histocompatibility complex class II (MHC II)...

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Detalles Bibliográficos
Autores principales: Brown, P J, Wong, K K, Felce, S L, Lyne, L, Spearman, H, Soilleux, E J, Pedersen, L M, Møller, M B, Green, T M, Gascoyne, D M, Banham, A H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777777/
https://www.ncbi.nlm.nih.gov/pubmed/26500140
http://dx.doi.org/10.1038/leu.2015.299