Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product

Bacteriophages produce endolysins, which lyse the bacterial host cell to release newly produced virions. The timing of lysis is regulated and is thought to involve the activation of a molecular switch. We present a crystal structure of the activated endolysin CTP1L that targets Clostridium tyrobutyr...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunne, Matthew, Leicht, Stefan, Krichel, Boris, Mertens, Haydyn D. T., Thompson, Andrew, Krijgsveld, Jeroen, Svergun, Dmitri I., Gómez-Torres, Natalia, Garde, Sonia, Uetrecht, Charlotte, Narbad, Arjan, Mayer, Melinda J., Meijers, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777826/
https://www.ncbi.nlm.nih.gov/pubmed/26683375
http://dx.doi.org/10.1074/jbc.M115.671172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777826/
https://www.ncbi.nlm.nih.gov/pubmed/26683375
http://dx.doi.org/10.1074/jbc.M115.671172

Ejemplares similares