Suppression of the invasive potential of Glioblastoma cells by mTOR inhibitors involves modulation of NFκB and PKC-α signaling

Glioblastoma (GBM) is the most aggressive type of brain tumors in adults with survival period <1.5 years of patients. The role of mTOR pathway is documented in invasion and migration, the features associated with aggressive phenotype in human GBM. However, most of the preclinical and clinical stu...

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Detalles Bibliográficos
Autores principales: Chandrika, Goparaju, Natesh, Kumar, Ranade, Deepak, Chugh, Ashish, Shastry, Padma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778030/
https://www.ncbi.nlm.nih.gov/pubmed/26940200
http://dx.doi.org/10.1038/srep22455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778030/
https://www.ncbi.nlm.nih.gov/pubmed/26940200
http://dx.doi.org/10.1038/srep22455

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