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Age-associated metabolic dysregulation in bone marrow-derived macrophages stimulated with lipopolysaccharide

Macrophages are major contributors to age-associated inflammation. Metabolic processes such as oxidative phosphorylation, glycolysis and the urea cycle regulate inflammatory responses by macrophages. Metabolic profiles changes with age; therefore, we hypothesized that dysregulation of metabolic proc...

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Detalles Bibliográficos
Autores principales: Fei, Fan, Lee, Keith M., McCarry, Brian E., Bowdish, Dawn M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778050/
https://www.ncbi.nlm.nih.gov/pubmed/26940652
http://dx.doi.org/10.1038/srep22637