An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles

The highly restrictive blood-brain barrier (BBB) plays a critically important role in maintaining brain homeostasis and is pivotal for proper neuronal function. The BBB is currently considered the main limiting factor restricting the passage of large (up to 200 nm) intravenously administered nanopar...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Nicole M., Gachulincova, Ivana, Ho, Diwei, Bailey, Charlotte, Bartlett, Carole A., Norret, Marck, Murphy, John, Buckley, Alysia, Rigby, Paul J., House, Michael J., St. Pierre, Timothy, Fitzgerald, Melinda, Iyer, K. Swaminathan, Dunlop, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778073/
https://www.ncbi.nlm.nih.gov/pubmed/26940762
http://dx.doi.org/10.1038/srep22595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778073/
https://www.ncbi.nlm.nih.gov/pubmed/26940762
http://dx.doi.org/10.1038/srep22595

Ejemplares similares