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Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development

Muscle stem cells (MuSCs) exhibit distinct behavior during successive phases of developmental myogenesis. However, how their transition to adulthood is regulated is poorly understood. Here, we show that fetal MuSCs resist progenitor specification and exhibit altered division dynamics, intrinsic feat...

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Detalles Bibliográficos
Autores principales: Tierney, Matthew Timothy, Gromova, Anastasia, Sesillo, Francesca Boscolo, Sala, David, Spenlé, Caroline, Orend, Gertraud, Sacco, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778082/
https://www.ncbi.nlm.nih.gov/pubmed/26904948
http://dx.doi.org/10.1016/j.celrep.2016.01.072