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Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development
Muscle stem cells (MuSCs) exhibit distinct behavior during successive phases of developmental myogenesis. However, how their transition to adulthood is regulated is poorly understood. Here, we show that fetal MuSCs resist progenitor specification and exhibit altered division dynamics, intrinsic feat...
Autores principales: | Tierney, Matthew Timothy, Gromova, Anastasia, Sesillo, Francesca Boscolo, Sala, David, Spenlé, Caroline, Orend, Gertraud, Sacco, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778082/ https://www.ncbi.nlm.nih.gov/pubmed/26904948 http://dx.doi.org/10.1016/j.celrep.2016.01.072 |
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