A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions

Sirtuins are NAD(+) dependent lysine deacylases involved in many regulatory processes such as control of metabolic pathways, DNA repair and stress response. Modulators of sirtuin activity are required as tools for uncovering the biological function of these enzymes and as potential therapeutic agent...

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Detalles Bibliográficos
Autores principales: Schuster, Sabine, Roessler, Claudia, Meleshin, Marat, Zimmermann, Philipp, Simic, Zeljko, Kambach, Christian, Schiene-Fischer, Cordelia, Steegborn, Clemens, Hottiger, Michael O., Schutkowski, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778124/
https://www.ncbi.nlm.nih.gov/pubmed/26940860
http://dx.doi.org/10.1038/srep22643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778124/
https://www.ncbi.nlm.nih.gov/pubmed/26940860
http://dx.doi.org/10.1038/srep22643

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