Cargando…

Use of (18)F-2-Fluorodeoxyglucose to Label Antibody Fragments for Immuno-Positron Emission Tomography of Pancreatic Cancer

[Image: see text] We generated (18)F-labeled antibody fragments for positron emission tomography (PET) imaging using a sortase-mediated reaction to install a trans-cyclooctene-functionalized short peptide onto proteins of interest, followed by reaction with a tetrazine-labeled-(18)F-2-deoxyfluoroglu...

Descripción completa

Detalles Bibliográficos
Autores principales: Rashidian, Mohammad, Keliher, Edmund J., Dougan, Michael, Juras, Patrick K., Cavallari, Marco, Wojtkiewicz, Gregory R., Jacobsen, Johanne T., Edens, Jerre G., Tas, Jeroen M. J., Victora, Gabriel, Weissleder, Ralph, Ploegh, Hidde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778250/
https://www.ncbi.nlm.nih.gov/pubmed/26955657
http://dx.doi.org/10.1021/acscentsci.5b00121