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A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16(INK4a) expression in head and neck squamous cell carcinoma patients

BACKGROUND: Human papilloma virus-16 (HPV-16) infection is a major risk factor for a subset of head and neck squamous cell carcinoma (HNSCC), in particular oropharyngeal squamous cell carcinoma (OPSCC). Current techniques for assessing the HPV-16 status in HNSCC include the detection of HPV-16 DNA a...

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Detalles Bibliográficos
Autores principales: Chai, Ryan C., Lim, Yenkai, Frazer, Ian H., Wan, Yunxia, Perry, Christopher, Jones, Lee, Lambie, Duncan, Punyadeera, Chamindie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778285/
https://www.ncbi.nlm.nih.gov/pubmed/26940728
http://dx.doi.org/10.1186/s12885-016-2217-1