Cargando…

A pilot study to compare the detection of HPV-16 biomarkers in salivary oral rinses with tumour p16(INK4a) expression in head and neck squamous cell carcinoma patients

BACKGROUND: Human papilloma virus-16 (HPV-16) infection is a major risk factor for a subset of head and neck squamous cell carcinoma (HNSCC), in particular oropharyngeal squamous cell carcinoma (OPSCC). Current techniques for assessing the HPV-16 status in HNSCC include the detection of HPV-16 DNA a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chai, Ryan C., Lim, Yenkai, Frazer, Ian H., Wan, Yunxia, Perry, Christopher, Jones, Lee, Lambie, Duncan, Punyadeera, Chamindie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778285/ https://www.ncbi.nlm.nih.gov/pubmed/26940728 http://dx.doi.org/10.1186/s12885-016-2217-1

Ejemplares similares

Salivary DNA methylation panel to diagnose HPV-positive and HPV-negative head and neck cancers
por: Lim, Yenkai, et al.
Publicado: (2016)

Current trends in the etiology and diagnosis of HPV-related head and neck cancers
por: Chai, Ryan C, et al.
Publicado: (2015)

Salivary miRNA panel to detect HPV-positive and HPV-negative head and neck cancer patients
por: Wan, Yunxia, et al.
Publicado: (2017)

The overexpression of salivary cytokeratins as potential diagnostic biomarkers in head and neck squamous cell carcinomas
por: Tang, Kai Dun, et al.
Publicado: (2017)

A Pilot Study into the Association between Oral Health Status and Human Papillomavirus—16 Infection
por: Sun, Charles Xiaohang, et al.
Publicado: (2017)

Unlocking the Potential of Saliva-Based Test to Detect HPV-16-Driven Oropharyngeal Cancer
por: Tang, Kai Dun, et al.
Publicado: (2019)

Oral HPV16 DNA as a screening tool to detect early oropharyngeal squamous cell carcinoma
por: Tang, Kai D., et al.
Publicado: (2020)

Determining the utility of a screening program to reduce the incidence of HPV driven oropharyngeal cancer
por: Vasani, Sarju, et al.
Publicado: (2021)

Oral HPV16 Prevalence in Oral Potentially Malignant Disorders and Oral Cavity Cancers
por: Tang, Kai Dun, et al.
Publicado: (2020)

Promoter Hypermethylation of Tumor-Suppressor Genes p16(INK4a), RASSF1A, TIMP3, and PCQAP/MED15 in Salivary DNA as a Quadruple Biomarker Panel for Early Detection of Oral and Oropharyngeal Cancers
por: Liyanage, Chamikara, et al.
Publicado: (2019)

Oral Microbiome: A New Biomarker Reservoir for Oral and Oropharyngeal Cancers
por: Lim, Yenkai, et al.
Publicado: (2017)

The saliva microbiome profiles are minimally affected by collection method or DNA extraction protocols
por: Lim, Yenkai, et al.
Publicado: (2017)

PD-L1 expressing circulating tumour cells in head and neck cancers
por: Kulasinghe, Arutha, et al.
Publicado: (2017)

Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
por: Huang, Xiaomin, et al.
Publicado: (2023)

High-risk HPV genotypes and P16INK4a expression in a cohort of head and neck squamous cell carcinoma patients in Singapore
por: Tan, Louise Soo Yee, et al.
Publicado: (2016)

HPV16 AND EXPRESSION OF PROTEIN P16(INK4A) AND E7 ONCOPROTEIN IN COLORECTAL CARCINOMA
por: PICANÇO-JUNIOR, Olavo Magalhães, et al.
Publicado: (2022)

The Performance of an Oral Microbiome Biomarker Panel in Predicting Oral Cavity and Oropharyngeal Cancers
por: Lim, Yenkai, et al.
Publicado: (2018)

An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma
por: Carper, Miranda B., et al.
Publicado: (2019)

Impact of label-free technologies in head and neck cancer circulating tumour cells
por: Kulasinghe, Arutha, et al.
Publicado: (2016)

Prevalence of HPV Infection and p16(INK4a) Overexpression in Surgically Treated Laryngeal Squamous Cell Carcinoma
por: Gallus, Roberto, et al.
Publicado: (2022)

Interaction of HPV16 and Cutaneous HPV in Head and Neck Cancer
por: Al-Soneidar, Walid A., et al.
Publicado: (2022)

The Use of Three-Dimensional DNA Fluorescent In Situ Hybridization (3D DNA FISH) for the Detection of Anaplastic Lymphoma Kinase (ALK) in Non-Small Cell Lung Cancer (NSCLC) Circulating Tumor Cells
por: Kulasinghe, Arutha, et al.
Publicado: (2020)

Comparison Between Two Detection Methods for HPV16, HPV18 and P16Ink4a Biomarkers in Diagnosis of Abnormal Cervical Cytology
por: Khazaei, Sedigheh, et al.
Publicado: (2016)

A HPV16-related prognostic indicator for head and neck squamous cell carcinoma
por: Zhang, Qian, et al.
Publicado: (2020)

Differences in the prognosis of HPV16-positive patients with squamous cell carcinoma of head and neck according to viral load and expression of P16
por: Biesaga, Beata, et al.
Publicado: (2017)

An Occult HPV-Driven Oropharyngeal Squamous Cell Carcinoma Discovered Through a Saliva Test
por: Tang, Kai Dun, et al.
Publicado: (2020)

Short term ex-vivo expansion of circulating head and neck tumour cells
por: Kulasinghe, Arutha, et al.
Publicado: (2016)

Head and neck cancer N-glycome traits are cell line and HPV status–dependent
por: Rasheduzzaman, Mohammad, et al.
Publicado: (2022)

Exploring the roles of HPV16 variants in head and neck squamous cell carcinoma: current challenges and opportunities
por: Cochicho, Daniela, et al.
Publicado: (2021)

A study on H-score threshold for p16ink4a immunoperoxidase expression in squamous cell tumours of oral cavity
por: Singh, Ravindra Pratap, et al.
Publicado: (2023)

Salivary micro RNAs as biomarkers for oropharyngeal cancer
por: Ekanayake Weeramange, Chameera, et al.
Publicado: (2023)

Highly Multiplexed Digital Spatial Profiling of the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma Patients
por: Kulasinghe, Arutha, et al.
Publicado: (2021)

Overexpression of p16(INK4a) Serves as Prognostic Marker in Squamous Cell Vulvar Cancer Patients Treated With Radiotherapy Irrespective of HPV-Status
por: Arians, Nathalie, et al.
Publicado: (2019)

HPV DNA in saliva from patients with SCC of the head and neck is specific for p16-positive oropharyngeal tumours
por: Wasserman, Jason K., et al.
Publicado: (2017)

Absence of deletions but frequent loss of expression of p16INK4 in human ovarian tumours.
por: Marchini, S., et al.
Publicado: (1997)

Characteristics and Impact of HPV-Associated p16 Expression on Head and Neck Squamous Cell Carcinoma in Thai Patients
por: Jiarpinitnun, Chuleeporn, et al.
Publicado: (2020)

Antibodies against human papillomavirus type 16 (HPV-16) and conjunctival squamous cell neoplasia in Uganda
por: Waddell, K, et al.
Publicado: (2003)

p16INK4A expression is frequently increased in periorbital and ocular squamous lesions
por: Kobalka, Peter J., et al.
Publicado: (2015)

Relevance research between the expression of p16(INK4a), Notch1, and hTERC genes: The development of HPV16‐positive cervical cancer
por: Huo, Wenyan, et al.
Publicado: (2020)

Correlation of EGFR, pEGFR and p16(INK4) expressions and high risk HPV infection in HIV/AIDS-related squamous cell carcinoma of conjunctiva
por: Mwololo, Anthony, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dpsi5gqqt1k6rafe0dsjuui5ud