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SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma

Cyclin D1 (CCND1) protein overexpression and/or the t(11;14)(q13;q32) translocation are the pathognomonic hallmarks of mantle cell lymphoma (MCL). However, there have been cases that lacked both t(11;14) and cyclin D1 protein but still had a gene expression profile suggesting a diagnosis of MCL. SOX...

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Detalles Bibliográficos
Autores principales: Narurkar, Roshni, Alkayem, Mohammad, Liu, Delong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778333/
https://www.ncbi.nlm.nih.gov/pubmed/26949534
http://dx.doi.org/10.1186/s40364-016-0060-9