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Measurement of free glucocorticoids: quantifying corticosteroid-binding globulin binding affinity and its variation within and among mammalian species

Plasma glucocorticoids (GCs) are commonly used as measures of stress in wildlife. A great deal of evidence indicates that only free GC (GC not bound by the specific binding protein, corticosteroid-binding globulin, CBG) leaves the circulation and exerts biological effects on GC-sensitive tissues. Fr...

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Detalles Bibliográficos
Autores principales: Delehanty, Brendan, Hossain, Sabrina, Jen, Chao Ching, Crawshaw, Graham J., Boonstra, Rudy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778445/
https://www.ncbi.nlm.nih.gov/pubmed/27293705
http://dx.doi.org/10.1093/conphys/cov020