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Cascade alkylarylation of substituted N-allylbenzamides for the construction of dihydroisoquinolin-1(2H)-ones and isoquinoline-1,3(2H,4H)-diones

An oxidative reaction for the synthesis of 4-alkyl-substituted dihydroisoquinolin-1(2H)-ones with N-allylbenzamide derivatives as starting materials has been developed. The radical alkylarylation reaction proceeds through a sequence of alkylation and intramolecular cyclization. The substituent on th...

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Detalles Bibliográficos
Autores principales: Qian, Ping, Du, Bingnan, Jiao, Wei, Mei, Haibo, Han, Jianlin, Pan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778529/
https://www.ncbi.nlm.nih.gov/pubmed/26977189
http://dx.doi.org/10.3762/bjoc.12.32