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Transcriptomic analysis of monocytes and macrophages derived from CLL patients which display differing abilities to respond to therapeutic antibody immune complexes

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia. While therapeutic antibodies show clinical activity in CLL patients, resistance inevitably develops resulting in treatment failure. Identifying mechanisms of antibody resistance and methods to reduce resistance would be valuable i...

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Detalles Bibliográficos
Autores principales: Burgess, M., Ellis, J.J., Mapp, S., Mollee, P., Mazzieri, R., Mattarollo, S.R., Gill, D., Saunders, N.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778605/
https://www.ncbi.nlm.nih.gov/pubmed/26981348
http://dx.doi.org/10.1016/j.gdata.2015.11.010