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Transcriptomic analysis of monocytes and macrophages derived from CLL patients which display differing abilities to respond to therapeutic antibody immune complexes
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia. While therapeutic antibodies show clinical activity in CLL patients, resistance inevitably develops resulting in treatment failure. Identifying mechanisms of antibody resistance and methods to reduce resistance would be valuable i...
Autores principales: | Burgess, M., Ellis, J.J., Mapp, S., Mollee, P., Mazzieri, R., Mattarollo, S.R., Gill, D., Saunders, N.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778605/ https://www.ncbi.nlm.nih.gov/pubmed/26981348 http://dx.doi.org/10.1016/j.gdata.2015.11.010 |
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