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Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood–brain barrier in vitro and in vivo

Brain glioblastoma and neurodegenerative diseases are still largely untreated due to the inability of most drugs to cross the blood–brain barrier (BBB). Nanoparticles have emerged as promising tools for drug delivery applications to the brain; in particular carbon nanotubes (CNTs) that have shown an...

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Detalles Bibliográficos
Autores principales: Kafa, Houmam, Wang, Julie Tzu-Wen, Rubio, Noelia, Klippstein, Rebecca, Costa, Pedro M., Hassan, Hatem A.F.M., Sosabowski, Jane K., Bansal, Sukhvinder S., Preston, Jane E., Abbott, N. Joan, Al-Jamal, Khuloud T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778610/
https://www.ncbi.nlm.nih.gov/pubmed/26809004
http://dx.doi.org/10.1016/j.jconrel.2016.01.031